TME KNOWLEDGE

Does Margin Width Affect Local Recurrence?

Effect of Margin Width on LR of Invasive Breast Cancer

 

n

LR%

Margin distance

   

0.1 – 1.0 mm

94

7%

1.1 – 2.0 mm

33

6%

2.1 – 5.0 mm

47

4%

> 5.0 mm

25

12%

Negative re-excision

101

8%

Unknown

41

7%

 

 

 

 

        21 large studies

        Over 14,000 patients

        4 year median follow-up

        Various statistical models

 

        Conclusions:

»        … margin width is not associated with local recurrence

»        …adjusting for adjuvant therapies removes any trend between margin width and local recurrence

 

 

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Tags: Margins

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