TME KNOWLEDGE

Margins in BCT

        Agreement - Transected tumor at the margin is “positive”

        No Agreement - What is a “negative margin”

Institute/Organization

DCIS

IDC

National Institute of Clinical Excellence (NICE)

2 mm

n/a

NCCN

> 1 mm

> 1 mm

European Society for Medical Oncology

> 2 mm

> 2 mm

New Zealand  Guidelines Group (NZGG)

> 2 mm

> 2 mm

German Cancer Society

> 5 mm

> 1 mm

NSAPB

No tumor on ink

No tumor on ink

 

 

Margin Status Definitions in Historical Trials comparing BCT to Mastectomy

 

NSABP

Tumor not on ink

NCI

Grossly negative (micro +)

Danish

Grossly negative (micro +)

EORTC 10801

Grossly negative (micro +)

Institut Gustave-Roussy

2 cm grossly normal tissue

Milan

2-3 cm normal tissue (micro +)

 

 

 

Project details

Tags: Margins

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