Genetic Risk Major Players: Regulation and Repair Group


n  PI3K


n  Akt


n  mTOR


n  ATM - ataxia telangiectasia mutated (“Lassie”)


n  PTEN - phosphatase and tensin homolog


n  RAD51 - radiation sensitive gene 51


n  PALB2 - partner and localizer of BRCA2


n  CHEK2 - CHK2 checkpoint homolog (“Timmy’s brother”)


n  BRIP1 - BRCA1-interacting protein 1


n  STK11 - serine threonine kinase 11


n  No Introduction Needed:


n  ER, HER2/ErbB, BRCA (“the Doctor”), p53 (“the Sheriff”)





Project details

Tags: Genetics and Testing

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