TME KNOWLEDGE

Genetic Risk Major Players: Regulation and Repair Group

 

n  PI3K

 

n  Akt

 

n  mTOR

 

n  ATM - ataxia telangiectasia mutated (“Lassie”)

 

n  PTEN - phosphatase and tensin homolog

 

n  RAD51 - radiation sensitive gene 51

 

n  PALB2 - partner and localizer of BRCA2

 

n  CHEK2 - CHK2 checkpoint homolog (“Timmy’s brother”)

 

n  BRIP1 - BRCA1-interacting protein 1

 

n  STK11 - serine threonine kinase 11

 

n  No Introduction Needed:

 

n  ER, HER2/ErbB, BRCA (“the Doctor”), p53 (“the Sheriff”)

 

 

 

 

Project details

Tags: Genetics and Testing

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